Topic: Sickle Cell
Recent research reveals how physical qualities -- and not only chemical ones may have an influence in determining how adult stem cells from the bone marrow develop into differentiated ones. The fi ... morePolitico reports that as "Congress prepares to return for a limited pre-election agenda, Rep. Diana DeGette (D-Colo.) said she has picked up wide support for her bill to permit embryonic stem-cell res ... more
Biologists at the University of California, San Diego have discovered that a gene critical for programmed cell death is also important in the loss of adult stem cells, a finding that could help to imp ... more
Biologists at the University of California, San Diego have discovered that a gene critical for programmed cell death is also important in the loss of adult stem cells, a finding that could help to imp ... more
Biologists at the University of California, San Diego have discovered that a gene critical for programmed cell death is also important in the loss of adult stem cells, a finding that could help to imp ... more
UT Southwestern Medical Center researchers have identified unique metabolic properties that allow a specific type of stem cell in the body to survive and replicate in low-oxygen environments. In a stu ... more
Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem ... more
The Association for Research in Vision and Ophthalmology (ARVO), a professional organization of member scientists, opposes the Federal District Court injunction that froze federal funding for human em ... more
The American Society for Biochemistry and Molecular Biology expressed its disapproval and disappointment this week in response to the Aug. 23 ruling in the U.S. District Court for the District of Colu ... more
Researchers say a judge's ruling jeopardizes millions of dollars in ongoing work as the argument about the merits of such study is reopened in court. ... more
Female induced pluripotent stem cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell r ... more
Biologists have discovered that a gene critical for programmed cell death is also important in the loss of adult stem cells, a finding that could help to improve the health and well-being of patients ... more
The phrase therapeutic hypothermia sounds like a contradiction in terms. How could hypothermia, or dangerously low body temperature, be therapeutic? Yet according to a recent Reuters article, a ... more
Millennium: The Takeda Oncology Company announced the publication of an article in the journal Blood describing the novel mechanism of action of MLN4924 through targeted pathway modulation in diffuse ... more
Vital progress in stem cell research by hundreds of U.S. laboratories is threatened after last week's injunction prohibiting federal funding for the study of human embryonic stem cells (hESCs). The pr ... more
Millennium: The Takeda Oncology Company announced the publication of an article in the journal Blood describing the novel mechanism of action of MLN4924 through targeted pathway modulation in diffuse ... more
Stem cells might be thought of as trunks in the tree of life. All multi-cellular organisms have them, and they can turn into a dazzling variety other cells - kidney, brain, heart or skin, for example. ... more
Dr. Eric A. Cohen, Director of the Human Retrovirology research unit at the Institut de recherches cliniques de Montreal (IRCM), and his team published yesterday, in the online open-access journal PLo ... more
In two closely related studies, two teams of Scripps Research Institute scientists have discovered the underlying mechanisms that activate a type of immune cell in the skin and other organs. The findi ... more
A study published in the journal Science shows how our bodies try to minimise potential 'collateral damage' caused by our immune system when fighting infection. The research may also provide new clues ... more
Scientists have devised a method for coaxing mouse embryonic stem cells into forming a highly specific motor neuron subtype. The research, published by Cell Press in the September 3rd issue of the jou ... more
New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study, published by Cell Press in the September 3r ... more
Scientists have built a clearer picture of how lengthy strands of DNA are concertinaed when our cells grow and divide, in a discovery could help explain how cell renewal can go wrong. Scientists have ... more
The Maryland Stem Cell Research Commission (Commission) will host the Third Annual Maryland Stem Cell Research Symposium in partnership with the National Institutes of Health (NIH) and the National In ... more
Stem cells might be thought of as trunks in the tree of life. All multi-cellular organisms have them, and they can turn into a dazzling variety other cells - kidney, brain, heart or skin, for example. ... more
In two closely related studies, two teams of Scripps Research Institute scientists have discovered the underlying mechanisms that activate a type of immune cell in the skin and other organs. The findi ... more
Scientists have built a clearer picture of how lengthy strands of DNA are concertinaed when our cells grow and divide, in a discovery could help explain how cell renewal can go wrong. Scientists have ... more
Major depression is a common and disabling brain condition marked not only by the presence of depressed mood but also by its effects on sleep, energy, decision-making, memory and thoughts of death or ... more
Researchers have identified unique metabolic properties that allow a specific type of stem cell in the body to survive and replicate in low-oxygen environments. ... more
Blood glucose monitoring is an important part of controlling diabetes, but the current method for glucose testing has some significant drawbacks. Patients test their blood glucose twice daily, reco ... more
Findings highlight need to vaccinate against H1N1, seasonal flu, researchers say ... more
Researchers have made a major breakthrough in finding out how aggressive cancers originate, raising hope of novel targeted therapies for future breast cancer patients, according to a study published i ... more
Researchers have made a major breakthrough in finding out how aggressive cancers originate, raising hope of novel targeted therapies for future breast cancer patients, according to a study published i ... more
Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insul ... more
Mayo Clinic researchers found that healthy young people who put on as little as 9 pounds of fat, specifically in the abdomen, are at risk for developing endothelial cell dysfunction. Endothelial cells ... more
Researchers have identified unique metabolic properties that allow a specific type of stem cell in the body to survive and replicate in low-oxygen environments. ... more
A cell phone text message -- and the buzz or beep that signals its arrival -- may not help a woman remember to pop her birth control pill, a new study suggests.Source: Reuters Health Related MedlinePl ... more
Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insul ... more
The Wall Street Journal: "The two scientists behind the lawsuit that has temporarily blocked federal funding for embryonic stem-cell research said Wednesday they were motivated by ethical objections t ... more
A cell devotes a significant amount of effort to maintaining the stability of its genome, preventing the sorts of chromosomal rearrangements characteristic of many cancers. Assays that measure the rat ... more
Athens, Ga. Stem cells might be thought of as trunks in the tree of life. All multi-cellular organisms have them, and they can turn into a dazzling variety other cellskidney, brain, heart or skin ... more
New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study, published by Cell Press in the September 3r ... more
Clinical trials for promising new drug candidate are planned LA JOLLA, CA August 30, 2010 An international team led by scientists from The Scripps Research Institute, the Swiss Tropical Instit ... more
A scientific breakthrough on how HIV takes control of cell division Montreal, September 3, 2010 Dr. Éric A. Cohen, Director of the Human Retrovirology research unit at the Institut de recherches c ... more
New findings may lead to the development of more effective therapies for inflammation, wounds and malignant tumors LA JOLLA, CA August 31, 2010 In two closely related studies, two teams of Scr ... more
The first study of Ewing's sarcoma that screened hundreds of genes based on how they affect cell growth has identified two potential anti-cancer drug targets, according to a scientific paper by the T ... more
New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study suggests that despite their "stem cell-like" ... more
A research team has shown for the first time that a gene called Myc, which is traditionally thought of as a cancer-causing gene, may be far more important in the development and persistence of stem ce ... more
In two closely related studies, two teams of scientists have discovered the underlying mechanisms that activate a type of immune cell in the skin and other organs. The findings may lead to the develop ... more
Scientists have built a clearer picture of how lengthy strands of DNA are concertinaed when our cells grow and divide, in a discovery could help explain how cell renewal can go wrong. ... more
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.A 62-year-old man is evaluated for an asymptomatic nodule on his shoulder that has been ... more
The Wall Street Journal: "The Obama administration asked a federal judge Tuesday to allow the government to continue funding embryonic stem-cell research while a case challenging the program makes its ... more
Detection of circulating and disseminated tumor cells in blood is a promising methodology to diagnose cancer dissemination or to follow up cancer patients during therapy. Today, the detection analyses ... more
Agensys, Inc., an affiliate of Tokyo-based Astellas Pharma Inc., announced that they have initiated a Phase I clinical trial of AGS-16M8F an antibody-drug conjugate (ADC) that is being developed for t ... more
Using readily available computer programs, researchers have developed a system to identify genes that will be useful in the classification of breast cancer. The algorithm, described in BioMed Central ... more
The National Institutes of Health this week ordered all of its researchers to immediately halt any experiments using human embryonic stem cells following a federal injunction. U.S. District Judge Royc ... more
A long-held assumption about asymmetrical division of stem cells has cracked. Researchers report that the mitotic spindle does not act alone -- that cortical proteins help to position a cleavage furro ... more
For the first time, it's possible to experimentally capture a global snapshot of the conformation of thousands of RNA molecules in a cell. The finding is important because this scrappy little sister o ... more
RNAi screening used for the first time to study Ewing #8217;s sarcoma PHOENIX, Ariz. Aug. 31, 2010 The first study of Ewing #8217;s sarcoma that screened hundreds of genes based on how they affe ... more
Studies show molecular imagings benefits in the evaluation and successful treatment planning for a wide spectrum of diseases Reston, Va. A series of studies published in the September Journal of N ... more
In Alzheimer #8217;s disease, the problem is beta-amyloid, a protein that accumulates in the brain and causes nerve cells to weaken and die. Drugs designed to eliminate plaques made of beta-amyloid ha ... more
Research reveals bacterial altruism makes populations stronger than individuals Drug resistant bacteria are a problem in many environments, especially healthcare institutions. While the ways in which ... more
A team of researchers, led by Yizheng Wang, at the Chinese Academy of Sciences, China, has identified a way to preserve nerve cells in a rat model of stroke. Stroke is most commonly caused by impaired ... more
Chemotherapy is the best broad defense against cancer recurrence after surgical resection. However, it is difficult to predict which patients will benefit from which regimen of anticancer drugs, if at ... more
Obama Administration Appeals Judge's Order Banning Stem Cell Research Cough Medicine Ingredient May Get New Restrictions: FDA Diabetes Top Reason for Vietna ... more
People who consume a variety of vegetables tend to have a lower risk of developing lung cancer compared to those who don't, according to a study published in the medical journal Cancer Epidemiology, B ... more
Adding a variety of vegetables to one's diet may help decrease the chance of getting lung cancer, and adding a variety of fruits and vegetables may decrease the risk of squamous cell lung cancer, espe ... more
New research in the FASEB Journal suggests that the #8216;Sprouty #8217; protein could be a therapeutic target for patients with obesity and/or osteoporosis, as well as diabetes, osteoarthritis and h ... more
A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils - the most abundant type of white blood cell - from ... more
A new and unique journal on cell transplantation aimed at helping translate laboratory findings into clinical applications is being launched by Cognizant Communication Corporation as a companion journ ... more
An Iowa State University team of researchers has developed a type of hybrid proteins that can make double-strand DNA breaks at specific sites in living cells, possibly leading to better gene replaceme ... more
Idera Pharmaceuticals, Inc. (Nasdaq: IDRA), announced that it has achieved a milestone under its worldwide licensing and collaboration agreement with Merck KGaA, Darmstadt, Germany. The milestone was ... more
Philadelphia, PA, 30 August 2010 - The notion that cutting or burning oneself could provide relief from emotional distress is difficult to understand for most people, but it is an experience reported ... more
Colon sloughs lining The intestines have to work properly if we are to benefit from the food we eat. Digestive juices must be secreted, the food broken down into smaller components and then transporte ... more
Researchers have tracked a cell-to-cell signaling pathway that designates the future location of the ear's sensory organs in embryonic mice. The scientists succeeded in activating this signal more wid ... more
Against a backdrop of some of the world's most sophisticated biological research labs, Rep. Steve Israel (D-Huntington) this morning issued a challenge to his colleagues in Congress: immediately upon ... more
A new study in mice shows how social support can help minimize some of the worst physical damages to the brain caused by a heart attack. From cell death to depressive symptoms to regulation of the hea ... more
Scientists have developed a new microfluidic tool for quickly and accurately isolating neutrophils -- the most abundant type of white blood cell -- from small blood samples, an accomplishment that cou ... more
Just kidding about the Catholic thing. The men are Ahmed Mohamed Nasser al Soofi, of Detroit, MI, and Hezem al Murisi, from Yemen... so as Rick suggests at the link, you know they're not Catholics, M ... more
Athens, Ga. Trypanosomes are parasites responsible for many human and animal diseases, primarily in tropical climates. One disease these parasites cause, African sleeping sickness, results from the ... more
CORVALLIS, Ore. New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling #8220;co-conspirators #8221; in the genesis of melanoma, in findings that co ... more
Researchers have found the first ever genetic risk factor associated with common types of migraine. The team found that patients with the DNA variant have a significantly greater risk for developing m ... more
In these lean times, smart consumers refuse to pay a lot for throwaway items, but will shell out a little more for products that can be used again and again. The same is true of bacteria and other mic ... more
The term "macrophage" conjures images of a hungry white blood cell gobbling invading bacteria. However, macrophages do much more than that: Not only do they act as antimicrobial warriors, they also pl ... more
The following summarizes selected women's health-related blog entries. ~ "Stem Cells, Politics and the Law," Michael Tomasky, The Guardian's "Michael Tomasky's Blog": The main issue in this week's emb ... more
Much of the world's electronic waste is being shipped to China for recycling and the cottage industry that has sprung up there to recover usable materials from computers, cell phones, televisions and ... more
The judicial injunction blocking federally funded human embryonic stem cell research not only blocks potential life-saving research but also threatens to undermine the system of peer-reviewed science ... more
Much of the world's electronic waste is being shipped to China for recycling and the cottage industry that has sprung up there to recover usable materials from computers, cell phones, televisions and ... more
Study highlights how blood profiling techniques could change patient care It may soon be possible to identify patients who will develop tuberculosis, as scientists have identified changes in the blood ... more
We need policy that allows the research to proceed, with federal dollars and with appropriate oversight.By Margaret AndersonExecutive Director, FasterCuresOn August 23, a federal judge blocked NIH fro ... more
Last year, researchers at the University of California, Irvine (UCI) announced that they had shown, for the first time, that adult neural stem cells could improve the memory of mice with advanced Alzh ... more
The largest clinical trial so far of intracoronary autologous stem-cell transplantation in patients with chronic heart failure has shown that such treatment was associated with multiple hemodynamic an ... more
Genetic variant may increase susceptibility to migraine triggers A world-wide collaboration of researchers has identified the first-ever genetic risk factor associated with common types of migraine. T ... more
Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabetes, a ... more
Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabetes, a ... more
International Stem Cell Corporation (OTCBB:ISCO), announced that the recent action of a federal district judge blocking federal funding of embryonic stem cell research is not expected to have negative ... more
Acidity (pH) in cells of baker's yeast, Saccharomyces cerevisiae, regulate the synthesis of cell membranes by controlling the production of enzymes that synthesize membranes. These are the findings of ... more
In a landmark study to be published in the journal Nature, scientists have been able to create the first picture of genetic processes that happen inside every cell of our bodies. Using a 3-D visualiza ... more
New research uncovers what may be a primary neuron-damaging insult that occurs in an inherited form of a devastating neurodegenerative disorder. The study, published by Cell Press in the journal Neuro ... more
Two new studies reveal that the commonly used insect repellents DEET and citronellal each work through a dual stimulation of insect sensory systems. The research findings, published by Cell Pres in th ... more
In a landmark study to be published in the journal Nature, scientists have been able to create the first picture of genetic processes that happen inside every cell of our bodies... ... more
Researchers have tracked a cell-to-cell pathway that designates the future location of the ear's sensory organs in embryonic mice. The scientists succeeded in activating this signal more widely across ... more
Nerve and cell regeneration occurred in nine of 10 patients. WebMD Health News ... more
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced that the European Commission has granted marketing authorisation for VPRIV(R) (velaglucerase alfa), a hu ... more
Newspapers across the country published editorials reacting to U.S. District Court Judge Royce Lamberth's recent ruling challenging the legality of the Obama administration's guidelines allowing feder ... more
NORFOLK, VA Researchers have isolated a molecule, small enough to be used as a drug, that can shut down a dysfunctional immune response that causes deadly hemorrhagic shock, results in delayed deat ... more
Study shows brain trauma associated with lifelong conditions that affect quality of life and mortality GALVESTON Traumatic brain injury, currently considered a singular event by the insurance indus ... more
A specific type of fat present in cell membranes also serves as a cellular pH sensor, a team of University of British Columbia researchers has discovered. pH is a measure of acidity or basicity. Cells ... more
Errors in the copying of genes during cell division can cause numerous diseases, including cancer. Yale School of Medicine scientists, however, have unraveled the secrets of a much more rare phenomeno ... more
Plant agents show promise in preventing skin cancer SAN ANTONIO, Texas, U.S.A. Scientists at The University of Texas Health Science Center San Antonio are on to something that should bring joy to s ... more
Human umbilical cord blood cells (HUCB) used to treat cultured rat brain cells (astrocytes) deprived of oxygen appear to protect astrocytes from cell death after stroke-like damage, reports a team of ... more
In a joint study conducted by Helmholtz Zentrum Munchen, the German Center for Neurodegenerative Diseases (DZNE) and a research group at Karolinska Institutet in Stockholm, Sweden, researchers have no ... more
In a joint study conducted by Helmholtz Zentrum Munchen, the German Center for Neurodegenerative Diseases (DZNE) and a research group at Karolinska Institutet in Stockholm, Sweden, researchers have no ... more
In a joint study conducted by Helmholtz Zentrum Munchen, the German Center for Neurodegenerative Diseases (DZNE) and a research group at Karolinska Institutet in Stockholm, Sweden, researchers have no ... more
NIH Director's Response to Stem Cell Injunction ... more
Despite clear evidence that Hsp12 -- a so-called heat shock or stress protein -- helps cells survive life-threatening conditions, how it works was an open question until now. The surprising answer is ... more
Errors in the copying of genes during cell division can cause numerous diseases, including cancer. Scientists, however, have unraveled the secrets of a much more rare phenomenon with potential therape ... more
The term "macrophage" conjures images of a hungry white blood cell gobbling invading bacteria. However, macrophages do much more than that: Not only do they act as antimicrobial warriors, they also pl ... more
A specific type of fat present in cell membranes also serves as a cellular pH sensor, researchers have discovered. ... more
Production of new nerve cells in the human brain is linked to learning and memory, according to a new study. The research is the first to show such a link in humans. The findings provide clues about p ... more
The Washington Post: "The National Institutes of Health announced Tuesday that it has suspended funding new human embryonic stem cell research and that all federally funded experiments already underwa ... more
The Department of Justice on Tuesday said it would appeal a U.S. District Court ruling that challenged the legality of the Obama administration's guidelines allowing federal funding for embryonic stem ... more
The American Association for Cancer Research (AACR), the world's oldest and largest cancer research organization, reiterates its support for the responsible conduct of human embryonic stem cell resear ... more
On August 23rd, a federal district judge issued a temporary ban on federal funding for embryonic stem cell research. Stem cell research holds great promise for the treatment of millions of Americans w ... more
In draft guidance published today (26 August 2010) NICE has recommended two treatments for multiple myeloma. Thalidomide (Thalidomide, Celgene) in combination with an alkylating agent and a corticoste ... more
In draft guidance published today (26 August 2010) NICE has recommended two treatments for multiple myeloma. Thalidomide (Thalidomide, Celgene) in combination with an alkylating agent and a corticoste ... more
A new study from researchers in Canada and Sweden has shown that biosynthetic corneas can help regenerate and repair damaged eye tissue and improve vision in humans. The results, from an early phase c ... more
New York, August 25, 2010A multicenter study has concluded that treatment with a new targeted therapy called PLX4032 (also called RG7204) resulted in significant tumor shrinkage in 80 percent of pat ... more
Findings add new dimension to how memories are encoded, suggest new therapeutic targets Functioning much like gears in a machine, cellular motor proteins are critical to dynamic functions throughout t ... more
The AACR (American Association for Cancer Research) has expressed concern that a recent Federal District Court injunction to stop federal funding for human embryonic stem cell research is a serious ob ... more
Researchers have managed to convert skin from individuals with metabolic diseases into liver cells using stem cell technology, according to an article published in the Journal of Clinical Investigatio ... more
Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells) as they hold promise for cel ... more
Scientists have created the first 3-D picture of genetic processes that happen inside every cell of our bodies. The picture is the first-ever image of a protein interacting with DNA in its tightly pac ... more
A federal injunction against funding human embryonic stem cell research came as a shock but will not stop more than A federal injunction against funding human embryonic stem cell research came as a sh ... more
New findings could lead to better treatments for memory disorders JUPITER, FL, August 24, 2010 - Scientists from the Florida campus of The Scripps Research Institute have discovered a mechanism that ... more
Study suggests potential for new oncolytic therapies LA JOLLA, CA-A novel mechanism used by adenovirus to sidestep the cell #8217;s suicide program, could go a long way to explain how tumor suppressor ... more
New research uncovers what may be a primary neuron-damaging insult that occurs in an inherited form of a devastating neurodegenerative disorder. The study, published by Cell Press in the August 26th i ... more
Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells), as they hold promise for ce ... more
Background: Albinism is a genetic disorder characterized by lack of skin pigmentation. It has a worldwide distribution, but is commoner in areas close to the equator like Nigeria. Skin cancers are a m ... more
Visit the new MedlinePlus Health Topic page on giant cell arteritis.Giant cell arteritis is a disorder that causes inflammation of arteries of the scalp, neck, and arms. The inflammation narrows the ... more
To their deep dismay, researchers discovered several years ago that laboratory samples of anaplastic thyroid cancer they were using to help them find new treatments for this lethal disease were probab ... more
Pathogens make themselves feel at home in the human body, invading cells and living off the plentiful amenities on offer. However, researchers reveal an opposite strategy used to ensure infection succ ... more
Experts say judge's injunction on using federal funds effectively halts work in labs across the country ... more
To their deep dismay, researchers at Mayo Clinic discovered several years ago that laboratory samples of anaplastic thyroid cancer (ATC) they were using to help them find new treatments for this letha ... more
Cellonis Biotechnologies, a Beijing and HK-based medical research and application company, has recorded some remarkable results in the treatment of a twelve-year-old boy with diabetes using their stem ... more
On Monday, U.S. District Court Judge Royce Lamberth issued a preliminary injunction that prohibits NIH from funding embryonic stem cell research under the new guidelines issued by the Obama Administra ... more
Cellonis Biotechnologies, a Beijing and HK-based medical research and application company, has recorded some remarkable results in the treatment of a twelve-year-old boy with diabetes using their stem ... more
To their deep dismay, researchers at Mayo Clinic discovered several years ago that laboratory samples of anaplastic thyroid cancer (ATC) they were using to help them find new treatments for this letha ... more
The human AIDS viruses (HIV-1 and HIV-2) originated as viruses of apes and monkeys, respectively, yet little is known about whether or how these invaders adapted to the new genetic #8220;environment ... more
Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5α that destroys HIV in rhesus monkeys. The finding could lead to new TRIM5α-based treatments that ... more
PHILADELPHIA Researchers from the University of Massachusetts Medical School have identified a novel approach of combining chemotherapy with a targeted therapy to decrease the recurrence of gliobla ... more
The SUN 1087 trial of Stutent (sunitinib malate) combined with erlotinib versus just elrotinib did not improve overall survival in patients with previously treated NSCLC (non-small cell lung cancer), ... more
Certain pathogens make themselves at home in the human body by invading cells and living off the plentiful amenities on offer there. However, researchers at the Max Planck Institute for Infection Biol ... more
The SUN 1087 trial of Stutent (sunitinib malate) combined with erlotinib versus just elrotinib did not improve overall survival in patients with previously treated NSCLC (non-small cell lung cancer), ... more
Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabetes, a ... more
Repeatedly boosting brain levels of one natural painkiller soon shuts down the brain cell receptors that respond to it, so that the painkilling effect is lost, according to a surprising new study that ... more
Experts say the injunction on using federal funds effectively halts work in labs across the country ... more
Accumulation of lipid peroxides in the cell are associated with diseases and cellular stress. In a new study, researchers show that lipid peroxides also play an important, yet unrecognized, role in th ... more
When human umbilical cord blood cells were used to treat cultured rat brain cells deprived of oxygen, the cells appeared to protect astrocytes from cell death after stroke-like damage. Researchers fou ... more
Joint Replacement Company Warned About Illegal Marketing: FDA Judge Calls Halt to Obama Policy to Expand Stem Cell Research Doctors Puzzled Over Muscle Dama ... more
Researchers at Johns Hopkins have shown that using specific drugs can protect nerve cells in mice from the lethal effects of Parkinson #8217;s disease. The researchers #8217; findings are published in ... more
Researchers find conflicting results on inflammatory processes Human umbilical cord blood cells (HUCB) used to treat cultured rat brain cells (astrocytes) deprived of oxygen appear to protect astrocyt ... more
Researchers have discovered that the opioid growth factor and its receptor, OGFr, a clinically important system with potent anti-tumor properties, has controlled entry from the cytoplasm to the nucleu ... more
When nicotine binds to the nicotinic acetylcholine receptor (nAchR), it is known to promote smoking addiction and may also directly promote the development of breast cancer, according to a new study. ... more
Tel Aviv University develops nano-vehicle to deliver chemotherapy treatments on target Chemotherapy, while an effective cancer treatment, also brings debilitating side effects such as nausea, liver to ... more
BOSTON (August 23, 2010) A clue to the causes of autism and mental retardation lies in the synapse, the tiny intercellular junction that rapidly transfers information from one neuron to the next. A ... more
Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Medical Research Council (MRC) have successfully used a drug to reset and restart the natural 24 hour b ... more
Human pluripotent stem cells, which can become any other kind of body cell, hold great potential to treat a wide range of ailments, including Parkinson's disease, multiple sclerosis and spinal cord in ... more
A UC Irvine study is the first to demonstrate that human neural stem cells can restore mobility in cases of chronic spinal cord injury, suggesting the prospect of treating a much broader population of ... more
New study shows GM-CSF reduces AD pathology and eliminates memory loss A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer #8217;s disease pathology and reversed th ... more
The DNA genomes of organisms whose cells possess nuclei are packaged in a highly characteristic fashion. Most of the DNA is tightly wrapped around protein particles called nucleosomes, which are conne ... more
A key step in understanding the origins of familial breast cancer has been made by two teams of scientists at the University of California, Davis. The researchers have purified, for the first time, th ... more
International Stem Cell Corporation (OTCBB:ISCO), announced that its stem cell therapeutic programs focused on protective, transparent corneas (CytoCor ) in the front of the eye and the light-sensit ... more
In the mouse model, the two drugs combined to eliminate the HIV virus Researchers at the University of Minnesota Academic Health Center have identified two drugs that, when combined, may serve as an e ... more
In the vast majority of patients with advanced cancer, their muscles will gradually waste away for reasons that have never been well understood. Now, researchers reporting in the August 20 issue of Ce ... more
Researchers at UT Southwestern Medical Center have uncovered a key weapon in the molecular arsenal the infectious bacterium Vibrio parahaemolyticus (V. para) uses to kill cells and cause food poisonin ... more
The internationally-renowned scientific journal Immunity, from the Cell Press group, published online recently, and will publish in its August 27 print issue, the results of a study conducted by a tea ... more
The first successful report of using cell-depleted lung as a natural growth matrix for generating new rat lung from embryonic stem cells is presented in a breakthrough article in Tissue Engineering, P ... more
ArQule, Inc. (Nasdaq: ARQL) and Daiichi Sankyo Co., Ltd. (TSE 4568) announced that they will move forward with a Phase 3 clinical trial of ARQ 197, a small molecule inhibitor of the c-Met receptor tyr ... more
In the vast majority of patients with advanced cancer, their muscles will gradually waste away for reasons that have never been well understood. Now, researchers reporting in the August 20 issue of C ... more
CD8 T-cell infiltration of the skin in HIV patients can look like lymphoma and was once thought to be malignant - but in fact it's a reactive nonmalignant syndrome that improves when the virus is cont ... more
Patients who receive a diagnosis of the skin cancer basal cell carcinoma at a younger age-along with those who have red hair, a higher socioeconomic status and a cancerous lesion on their upper extrem ... more
The DNA in the cell nuclei of higher organisms is tightly coiled around protein complexes called nucleosomes, which repress gene expression. Researchers in Germany have now developed a model that expl ... more
ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops antibody-based targeted anticancer products, today announced that the US Food and Drug Administration (FDA) has granted orphan dru ... more
Patients who receive a diagnosis of the skin cancer basal cell carcinoma at a younger age-along with those who have red hair, a higher socioeconomic status and a cancerous lesion on their upper extrem ... more
Research demonstrates that drug and radiotherapy treatment saves lives A medical researcher at the University of Leicester has made a significant advance in the treatment of cervical cancer. Dr Paul ... more
New Rochelle, NY, August 19, 2010The first successful report of using cell-depleted lung as a natural growth matrix for generating new rat lung from embryonic stem cells is presented in a breakthrou ... more
Scientists are closer to understanding what triggers muscle damage in one of the most common forms of muscular dystrophy, called facioscapulohumeral muscular dystrophy (FSHD). FSHD affects about 1 in ... more
UCI study is first to show reversal of long-term hind-limb paralysis Irvine, Calif., Aug. 19, 2010 A UC Irvine study is the first to demonstrate that human neural stem cells can restore mobility in ... more
Fungal and bacterial pathogens are well capable of infecting plants, animals and humans despite their immune systems. Fungi penetrate leafs, stalks and roots, or skin, intestines and lungs, to infect ... more
Researchers report the first successful use of cell-depleted lung as a natural growth matrix for generating new rat lung from embryonic stem cells. ... more
Montreal, August 19, 2010 The internationally-renowned scientific journal Immunity, from the Cell Press group, publishes online today, and will publish in its August 27 print issue, the results of ... more
In the vast majority of patients with advanced cancer, their muscles will gradually waste away for reasons that have never been well understood. Now, researchers reporting in the August 20 issue of Ce ... more
Mayo Clinic researchers found that healthy young people who put on as little as 9 pounds of fat, specifically in the abdomen, are at risk for developing endothelial cell dysfunction. Endothelial cells ... more
Immature human nerve cells grew in the spines of injured mice and helped them walk a little better, researchers said on Wednesday in a study they said shows it may be possible to treat patients weeks ... more
Researchers have developed an improved coating technique that could strengthen the connection between titanium joint-replacement implants and a patients' own bone. The stronger connection -- created b ... more
Alzheimer's disease destroys brain cells and their connections (called synapses), causing memory loss and other cognitive problems that disrupt work, hobbies and daily life. Symptoms can be alleviated ... more
The antiabortion-rights group Hawaii Right to Life said it will not endorse GOP Rep. Charles Djou because he supports federally funded human embryonic stem cell research and has said that Roe v. Wade ... more
A nuclear protein of previously unknown function has been shown to regulate the migration of tumor cells in the spread of melanoma, the most deadly form of skin cancer. Researchers at the RIKEN Advanc ... more
Are there too many stem cell research journals? This question has been posed by Drs. Paul Sanberg and Cesar Borlongan of the Department of Neurosurgery and Brain Repair at the University of South Flor ... more
Sanford-Burnham scientists uncover new clues to the molecular action of memantine, a drug used to treat Alzheimer #8217;s disease, that show why side effects are rare Alzheimer #8217;s disease destroy ... more